COMPENSATION: Competitive with share options available
LOCATION: BioEscalator, Old Road Campus, Oxford
HOURS: Full-time

NUCLEOME THERAPEUTICS, a fast-growing biotech start-up that is leveraging a proprietary gene regulation platform, based on a decade of world-leading research from Oxford University, to unlock the non-coding genome for drug target discovery and development.

Its proprietary platform combines machine learning and novel molecular biology techniques that define the 3D structure of the genome and enables variant functional validation at scale. The company is focused initially on developing novel treatments for autoimmune diseases related to lymphocytes.

We are seeking a Target Discovery Lead (Computational Biologist, Data Scientist) who is a self-starter, proactive and would like to work in a dynamic environment of a start-up. The successful candidate will help us triage the most promising targets identified by our propriety technology into a portfolio of drug discovery programs, assessing druggability, effectiveness and impact as well as the competitive landscape to inform the choices. You’ll act as the link between the company’s computational and platform technology scientists and use your excellent lab skills to validate these novel targets in vitro, playing a critical role in determining the therapeutic potential of these novel targets. As an independent thinker you will plan and implement experiments, interpret the data, and distil complexity into concise communication, while providing scientific coaching and mentorship for less experienced team members. You will have an integral role in the venture, take ownership of the work and demonstrate an exceptional work ethic towards discovering breakthrough medicines that will improve patients’ lives.

For more information download the full details here.