Job description

This is an exciting opportunity to join a vibrant research team that combines expertise in bioinformatics and computational design, peptide and protein chemistry, and product commercialisation. The position is initially fixed term, as part of a specific NIHR grant-funded project, which runs for 6 months from 1^st July to 31^st December 2023, with potential for full time conversion in 2024.

In this post, you will develop and test new peptide and fluorophore components to incorporate into Rosa’s core sensing platform, Pandra. This is with the specific aim of creating sensor arrays compatible with instrumentation widely utilised in a clinical laboratory setting. The produced sensor arrays would then be trained and tested for the detection of chronic liver disease in patient serum. In addition, we are a small and nimble company with flexibility being highly valuable to us.  As such, from time-to-time, you may be required to briefly switch to working on other projects to meet broader deadlines.

We are seeking exceptional candidates with a PhD in Biochemistry, Chemistry, Bioengineering or a related discipline. Expertise in one or more of fluorescence spectroscopy, protein-ligand interactions, biophysics, peptide/protein handling, biosensing and qPCR would be a distinct advantage, and applicants with multiple of these skill sets are encouraged to apply.  We are keen to receive applications from ambitious, and energetic individuals with an interest in translating laboratory-based research into real-world applications.

Roles and responsibilities

Research responsibilities

• Assisting with all aspects of research conducted in the laboratory as and when required
• Keeping accurate records of experimental procedures, workflows, and data
• Analysing and interpreting data and presenting work in a clear and concise fashion at regular company meetings and to external collaborators
• Testing new and existing peptide and fluorophore sensor components
• Training and testing newly developed sensor arrays to differentiate patient serum samples

Person specifications

Relevant skills & experience

Essential

• An ambitious team player who can conduct themselves in a polite, respectable, and professional manner when dealing with others
• Extensive practical laboratory experience
• Ability to formulate and execute an experimental work plan
• A demonstrable ability to innovate and think laterally
• An ability to work independently and as part of a team
• An ability to forge new collaborative partnerships and to work alongside third parties
• Ability to take accurate records of work carried out
• Ability to liaise and communicate effectively with a wide variety of internal and external contacts
• Excellent numeracy and literacy, and computer literacy

Desirable

• Experience with qPCR assays, instrumentation and data analysis
• Fluorescence assay development
• Expertise in the handling and analysis of fluorescent molecules
• Biophysical analysis of peptides/proteins
• Experience with the handling and analysis of biological fluids
• Experience with high-throughput assays and functional assays of peptides/proteins
• Experience working with peptide/protein array technologies
• Experience working with robotics and automation pipelines
• Experience with computational ligand docking and/or other computational methods of probing protein-ligand interactions

• A keen interest in learning computer programming and scripting
• Experience in using electronic notebooks
• Experience of working in a multidisciplinary team in an early-stage company
• Experience of GLP, GMP and/or GCLP

Relevant qualifications

Essential

• A PhD in Biochemistry, Chemistry, Bioengineering or a related discipline, or equivalent research experience

Job title:                      Research Scientist

Reporting to:               CTO

Location:                     Science Creates, St Philips Central, Bristol, UK

Hours of work:             Full time, for 6 months, with the potential to move to permanent.

Closing date:             2^nd May 2023

Benefits package:       £32,000 - £35,000, dependent on experience

Expected start date:    1^st July 2023

Job title: Research Scientist
Reporting to: CTO
Location: Science Creates, St Philips Central, Bristol, UK
Hours of work: Full time, for 6 months, with the potential to move to permanent.
Closing date: 2nd May 2023
Benefits package: £32,000 - £35,000, dependent on experience
Expected start date: 1st July 2023
 

How to apply

Please send your CV with a cover letter to: admin@rosabio.tech, including "Job application – Research Scientist" in the subject line to apply for this role.  

The deadline for application is 2nd May 2023 at 5 pm UK time.
Successful candidates will be contacted for an interview within 1 week of the closing date.